Author

Sanzhong Li

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Review Open access Sep 2026

Oncolytic bacteria therapy for malignant glioma

Malignant glioma is a group of primary malignant tumors of the central nervous system with an extremely poor prognosis, with glioblastoma being the most malignant type. Its highly invasive nature, tumor heterogeneity, stubborn immunosuppressive microenvironment, and the barrier effect of the blood-brain barrier result...

Fei-Yue Li, Jing Zhao, Ang Ji et al. · Frontiers in Immunology · 0 citations

Open access Aug 2026

Hypoxic Endothelial-Cell-Derived Exosomal lnc-DKK3 Reprograms Tumor-Associated Macrophages via USP47/PD-L1/RelA Axis to Promote Glioma Progression

The hypoxic microenvironment in gliomas critically contributes to malignant progression. This study investigates the functional role and molecular mechanisms of long noncoding RNAs derived from hypoxic endothelial cell exosomes in reprogramming tumor-associated macrophages and driving glioma progression. We identified...

Zan-Han Wang, Yong-Bo Zhao, Fan Fan et al. · Research · 0 citations