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Author

Sara G. F. Ferreira

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Open access Sep 2026

The Gordian Knot Enhances Ubiquitin Binding in UCH-L1

The results suggest that the 52 knot in UCH-L1 is not a passive topological feature but a functional element that constrains unfolding dynamics and contributes to substrate binding efficiency.

Sara G. F. Ferreira, P. Faísca, M. Machuqueiro · 0 citations

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