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Author

Sarah Adi Eisdorfer

1 paper indexed here

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Open access Oct 2026

Targeting tumor-selective membrane-associated PCNA enables selective antibody–drug conjugate therapy

ABSTRACT Membrane-associated proliferating cell nuclear antigen (mPCNA) is an attractive tumor-selective antigen for antibody–drug conjugate (ADC) development. We generated a chimeric IgG1 ADC, RC14-MMAE, to exploit three key properties of mPCNA that support its use as an efficient delivery platform. First, flow-cytome...

Muhammad Abu-Ahmad, Nir Miriam Ungar-Malma, A. Naumchik et al. · 0 citations

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