Author

Sarah Smith

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Open access Aug 2026

NMR metabolomics and glycomics for cancer detection in patients with non-specific symptoms: a prospective observational cohort study

Summary Background Early cancer diagnosis in patients with non-specific symptoms is limited by the lack of discriminatory tests. Within the Oxfordshire Suspected CANcer (SCAN) pathway, exploratory biomarker work showed that serum 1H NMR-based metabolomics can identify cancer with high accuracy. SCAN2 evaluated whether...

T. Kacerova, A. Yates, J. Larkin et al. · EBioMedicine · 0 citations

Open access Aug 2026

Peripheral blood microarray-based transcriptomic and epigenetic analyses identify immune, inflammation, and metabolic dysregulation in Alzheimer’s disease

Leveraging multi-omics to better understand the molecular signatures and pathways underlying Alzheimer’s disease (AD) pathogenesis is critical for early diagnosis and disease modifying interventions. We performed peripheral blood transcriptome (N = 669) and epigenome microarray analyses (N = 553) on non-Hispanic white...

Brendan A. Mitchell, I. Hausle, Sarah Smith et al. · npj Dementia · 0 citations