Chirality-Matched Cyclopropenimine–Thiourea Organocatalysis for Regiocontrolled Ring-Opening Polymerization of Methyl Glycolide
Poly(lactic-co-glycolic acid) (PLGA) is widely used in biomedical applications owing to its high biodegradability and biocompatibility. Although the ring-opening polymerization (ROP) of methyl glycolide (MeG) offers a route to synthesizing alternating PLGA, the comparable reactivity of its two electrophilic ring-open...