Deciphering the molecular recognition of advantame by calf thymus DNA and human serum albumin through integrated multispectroscopic and molecular docking analyses.
Advantame (ADV), a highly potent aspartame-derived non-nutritive sweetener, has been increasingly used as a food additive, while its molecular interactions with biological macromolecules remain insufficiently characterized. In this study, the binding behavior of ADV, a next-generation high-intensity sweetener, toward c...