Saulo Gabriel Do Nascimento Della Coleta

Exercise elicits mitonuclear protein imbalance and UPRmt in the liver of mice with obesity

Mitochondrial dysfunction plays a critical role in the development of metabolic dysfunction-associated steatotic liver disease (MASLD). It has been proposed that mitochondrial unfolded-protein response (UPRmt) activation improves mitochondrial function in the liver. Growing evidence demonstrates that physical exercise...