BTK Inhibition Resets Pathological B and T cell Subsets in Patients with IgG4-Related Disease 2258804
IgG4-related disease (IgG4-RD) is a fibroinflammatory disorder marked by tissue infiltration of IgG4+ plasmablasts (PB) and elevated serum IgG4 levels. Bruton’s Tyrosine Kinase inhibition (BTKi) blocks key signaling pathways in B cells and showed promising efficacy in other autoimmune diseases. This is the first...