Saurabh Srivastava

Hyaluronic acid-navigated nanoplatforms for oral cancer management: Current advances, translational perspectives, and future outlook-A review.

Oral cancer represents a significant global health burden exacerbated by aggressive tumor behavior and inadequate therapeutic outcomes, collectively contributing to high morbidity and mortality rates. Current treatment modalities, including surgery, radiotherapy, and chemotherapy, are often limited by a lack of tumor s...

Cell targeting peptide guided nanomedicine: a new paradigm in precision oncology for the management of non-small cell lung cancer.

Non-Small Cell Lung Cancer (NSCLC) remains a leading cause of cancer-related mortality worldwide owing to its high prevalence, metastatic potential, therapeutic resistance and poor survival outcomes. Effective management of NSCLC is hindered by the heterogeneous tumor microenvironment (TME), non-selective drug biodistr...

Intranasal Delivery of Piceatannol-Loaded Liposomes for Glioblastoma Management: Formulation Optimization, In Vitro, Ex Vivo, In Ovo and LC-MS/MS- Based In Vivo Pharmacokinetic and Brain Distribution Assessment

Rational Coformer Screening of Multicomponent Crystals of Abiraterone Acetate Using Machine Learning (ML) and Multicomponent Hydrogen Bond Propensity (MCHBP): A Comprehensive Structural and Computational Investigation

Multicomponent crystalline systems offer a viable approach to improving the physicochemical and pharmacokinetic properties of drugs, thereby enabling the rational optimization of solid forms through coformer identification. The conventional process relies on empirical knowledge and chemical intuition. To overcome tra...

Unlocking exosome potential: Comprehensive review on diagnostic, prognostic and therapeutic approaches in melanoma.

Exosome-based strategies hold substantial potential for improving the diagnosis and management of melanoma, which may encourage the development of next-generation therapeutic interventions in the medical world.

Intranasal Pacritinib-loaded nanoemulsion for Glioblastoma management: In Vitro, ex Vivo, 3D spheroid and In vivo brain biodistribution studies.

It can be concluded that PAC-NE is a non-invasive delivery system which shows promising results for better brain delivery thereby supporting the clinical translation of PAC for GBM therapy.