Author

Sayan Das

2 papers indexed here

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Open access Sep 2026

Integrating NMR and contact-response analysis reveals the allosteric network driving domain closure in Enzyme I

It is shown that ligand binding reshapes a distributed network of coupled interactions that spans the active site, interdomain linker, and domain interfaces, driving domain closure, and independent perturbations converge on the same network, demonstrating that it reflects intrinsic features of the protein energy landsc...

Aayushi Singh, Daniel Burns, Sergey L. Sedinkin et al. · Proceedings of the National... · 0 citations

Open access Jul 2026

1H, 15N, 13C backbone resonance assignment of Escherichia coli AlkB in complex with Zn(II) and α-ketoglutarate

The backbone 1H, 15N, 13C chemical shift assignment of E. coli AlkB in complex with Zn2+ and α-ketoglutarate is reported, allowing investigations of the protein structural dynamics anticipated to provide crucial insight regarding fundamental aspects in the recognition and enzyme regulation processes.

Sayan Das, J. Purslow, Kyle Malcom et al. · Biomolecular NMR Assignments · 0 citations