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Author

Sayan Paul

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Review Open access Sep 2026

The mitochondrial theory of sleep: an integrative framework for understanding sleep-wake regulation

Sleep is an essential biological function with unclear mechanisms. Recent research links the circadian clock, energy metabolism, calcium handling, reactive oxygen species (ROS) production, and synaptic plasticity to cognitive performance. Given that mitochondria regulate cellular energy production, calcium buffering, a...

Seithikurippu R. Pandi-Perumal, Sayan Paul, K. Saravanan et al. · 0 citations
Review Open access Jul 2026

Cell-Based Therapies for Cardiac and Vascular Regeneration in Cardiovascular Disease: Recent Advances, Translational Barriers, and Future Directions

This review examines the full range of cell-based strategies studied to date, the clinical trial evidence, the barriers to progress, and what engineered vesicles, bioengineered tissue constructs, gene editing, and improved trial design might offer.

Sayan Paul, Raj Wasnik, Ranjith Kumavath et al. · 0 citations

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