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Scott B. Rothbart

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Open access Aug 2026

Histone modification cross talk between a host and pathogen

Significance Bacterial pathogens reprogram host gene expression by delivering effector proteins that modify chromatin, but it is not known how the host epigenetic environment impacts effector function. Here, we show that the Legionella effector RomA senses and responds to the host’s existing epigenetic landscape and is...

Shantinique S. Miller, Joel A. Hrit, Scott B. Rothbart et al. · 0 citations
Open access Jul 2026

A Derivatization-Free Parallel Reaction Monitoring-Based Proteomics Workflow for Quantitative, Site-Specific Analysis of Histone Post-Translational Modifications

A derivatization-free parallel reaction monitoring (PRM) workflow for robust, quantitative, and site-specific analysis of major histone H3 and H4 PTMs, enabling reliable validation of selected histone PTMs.

Hyoungjoo Lee, Ashley K. Wiseman, Bailey M. Tibben et al. · 0 citations

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