Author

Scott Shurmur

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Review Open access Aug 2026

Antibody–Drug Conjugates in Contemporary Oncology: A Clinical Perspective on Dose Optimization, Sequencing, and Combination Strategies

This review examines the structural and biologic features that determine clinical activity, including target selection, linker stability, payload class, drug-to-antibody ratio, tumor penetration, biomarkers, toxicity, and resistance.

A. Philipovskiy, Scott Shurmur, Muhammad Bilal Abid · Cancers · 0 citations