Open access
Sep 2026
The rhomboid-like pseudoprotease TMEM115 defines a two-factor mechanism for Rab6A effector recruitment
It is shown that the rhomboid-like pseudoprotease TMEM115 defines an unexpected two-factor system with Rab6A to target the golgin TMF1, and proposed that two-factor effector recruitment defines a mechanism for precise Rab GTPase-mediated membrane targeting.
Bo-Ya Zhang, O. Bryant, Nadine Muschalik et al.
· bioRxiv · 0 citations