Open access
Aug 2026
Ank3 loss in adult forebrain excitatory neurons disrupts behavior, neuronal activity, membrane proteome, and myelination.
These findings identify ankyrin-G as a molecular bridge between excitatory neuronal activity, synaptic structure, and myelin-associated protein expression, revealing a pathway by which ANK3 variants may contribute to neuropsychiatric disease.
Sehyoun Yoon, Marc Dos Santos, Natalia Khalatyan et al.
· Proceedings of the National... · 0 citations