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Seiya Watanabe

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Open access Oct 2026

Structural basis for oxidation-coupled isomerization by ApnO.

D-Apionate oxidoisomerase (ApnO), involved in D-apiose metabolism from bacteria, is one of the few examples of the enzymes that catalyze two different reactions within a single active site, whereas there is no functional orthologue with significant sequence identity. Based on genome context, we found that ApnO addition...

Seiya Watanabe, Yuzuki Aono, S. Terawaki et al. · 0 citations

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