Author

Semiha Köprü

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Open access Sep 2026

A New Series of Imidazole Based Hydrazones as Potent Anti-Diabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition and Molecular Docking Studies

In the present study, new multifunctional imidazoles which contains the synthesis and biological activity experiments have been reported as α-glucosidase inhibitors. The procedure of imidazole-hydrazone derivative compounds (ISA1-5) relies on the condensation reaction of 5-Cl isatin and 2-benzylidenehydrazinecarboximid...

Semiha Köprü · Bitlis Eren Üniversitesi Fen... · 0 citations

Aug 2026

Synthesis of Novel 4,6‐Dimethoxyindole‐Based Hydrazones Derived From 2,4‐Dimethoxybenzaldehyde: Design, Cytotoxic Activity, Molecular Docking, and ADME‐Tox Studies

In silico ADME‐toxicity analyses predicted acceptable physicochemical and pharmacokinetic properties, supporting the potential of these derivatives as promising anticancer candidates.

Reşit Çakmak, Eyüp Başaran, Senem Akkoç et al. · ChemistrySelect · 0 citations