Paradoxical prognosis of extracellular vesicle-derived miR-4435 expression in advanced colorectal cancer
Extracellular vesicle (EV)-derived microRNAs are promising non-invasive biomarkers for colorectal cancer (CRC), but their stage-specific prognostic significance remains unclear. We evaluated circulating EV-derived miR-4435 and its target TIMP3 in a retrospective cohort of 100 plasma samples (20 healthy controls and 8...