Author

Seong-Gyu Ko

2 papers indexed here

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Open access Oct 2026

Anti-inflammatory effects of JI-017 in cellular and an LPS-induced endotoxemia model

JI-017 significantly reduced nitric oxide production and suppressed inflammatory cytokine and chemokine expression in LPS-stimulated RAW 264.7 macrophages and was associated with improved survival and attenuated systemic and hepatic inflammatory responses in an LPS-induced endotoxemia model.

Young-Ha Kim, Sang-Eun Lee, Ga-Eun Choi et al. · Molecular Biology Reports · 0 citations

Open access Aug 2026

JI-CS004, a chloroform fraction of SH003, induces reactive oxygen species-dependent intrinsic apoptosis via endoplasmic reticulum stress-associated mitochondrial dysfunction in human colorectal cancer cells

Conventional therapies for colorectal cancer (CRC) are often limited by toxicity and therapeutic resistance. Alternative therapeutic strategies are therefore needed. Natural product-derived compounds have been explored as potential anticancer agents. The molecular mechanisms underlying the anticancer effects of JI-CS00...

Taehyoun Kim, Kwang-Jin Cho, H. Hwang et al. · Molecular Biology Reports · 0 citations