Open access
Aug 2026
Small-Molecule Activators of PRMT1: Discovery, SAR Analyses, and Proapoptotic Effects in Pancreatic Cancer Cells
TR-07 is established as the first selective, cell-active PRMT1 activator and underscores the therapeutic promise of this novel class of modulators.
Sepideh Salehipour-Bavarsad, Christian Iking, Jonas Kammertöns et al.
· Journal of Medicinal Chemist... · 0 citations