Author

Sergey Vladimirov

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Review Open access Oct 2026

The CXCL12/CXCR4 axis in breast cancer-associated fibroblasts: a transcriptome analysis and systematic literature review

It is hypothesised that the CXCR4 High -CAF transcriptome profile is compatible with a biologically plausible theory of transition between paracrine and autocrine regulatory modes and inflammatory cell states, and suggests a possible shift from TGF-β-dependent to CXCR4-mediated regulation of CXCL12.

Sergey Vladimirov, David Sergeevichev, M. Bogachek et al. · Frontiers in Bioengineering... · 0 citations

Open access Jul 2026

Reconstructing the glioblastoma microenvironment in heterotypic 3D spheroids: a multicellular model to study tumor-stromal crosstalk

These heterotypic 3D spheroid models offer a stroma-enriched, reproducible platform for the analysis of stromal contributions to glioma progression and for exploratory preclinical evaluation of therapeutic strategies.

Y. Nikitina, Alina Kazakova, A.A. Leonteva et al. · Frontiers in Bioengineering... · 0 citations