Sergio G.-M. Alcantara

High-resolution binding data of TFIID and cofactors show promoter-specific differences

TFIID is instrumental in recognizing promoter sequences and initiating transcription, yet a cohesive understanding of how this complex engages and functions at different promoter types in vivo is still lacking. Here, we employed ChIP-nexus to capture high-resolution binding footprints of all Drosophila TFIID subu...