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Serina L. Robinson

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Review Open access Sep 2026

Advancing biosynthetic pathway discovery through short-read-directed long-read sequencing.

It is argued that the increasing availability of MAGs recovered from short-read metagenomes with recent advancements in ultra-low input DNA amplification for high-fidelity PacBio sequencing-now requiring as little as nanograms of DNA-can be used sequentially to boost biosynthetic pathway discovery.

M. Gabrielli, Agathe Bredel, L. Paoli et al. · 0 citations
Open access Sep 2026

EnZight: A Structure-Guided Algorithm to Identify and Prioritize Substitution Hotspots for Enzyme Engineering

Homologous protein structures contain valuable information about tolerated sequence variation. However, translating this information into practical enzyme design strategies remains challenging. Here we present EnZight, a user-friendly web server that integrates homologous structural alignment with intuitive visualizati...

R. R. Østergaard, Mikkel Lyskjær Jensen, Suzana Siebenhaar et al. · 0 citations

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