In silico Study of Bioactivity and Potential of Small Molecules from Manalagi Apple (Malus sylvestris L. Mill.) as Inhibitors of Trimethylamine-N-Oxide (TMAO) Precursors
Targeting the precursors of trimethylamine-N-oxide(TMAO), such as choline, betaine, and enzymes produced by the FMO3 gene, through natural compounds may reduce risk factors such as cardiovascular and metabolic diseases. Protein precursors involved in high TMAO level production include cntA, CUTC, and FMO3. Manalagi app...