Seunghwan Oh

Human Skin Permeability Prediction by Machine Learning for Transdermal Drug Delivery

Background and Objectives: The dose a transdermal patch delivers is governed by the drug’s permeability coefficient (Kp) across skin, and the reference Potts–Guy equation assumes log Kp is linear in lipophilicity and molecular weight. Whether that form holds across the whole of the public human data, and how far such a...