Protective effect of linalool against morphine-induced renal injury: Modulation of oxidative stress and PI3K/AKT/L-FABP signaling pathway
Objective(s): Opioid misuse and prolonged therapeutic use are increasingly linked to systemic toxicities, including renal dysfunction. Morphine has been shown to induce oxidative stress and disrupt intracellular signaling pathways implicated in kidney injury. Linalool, a naturally occurring monoterpene with antioxidant...