Seyedeh Zohreh Mirjalili

Novel diazene-tri(phenoxy-1,2,3-triazole-acetamide) derivatives as potent α-glucosidase inhibitors: synthesis, biological evaluation, and in silico studies

α-Glucosidase is a key therapeutic target for treating type 2 diabetes mellitus. A new series of novel diazene-tri(phenoxy-1,2,3-triazole-acetamide) derivatives 9a–p was designed by hybridizing previously reported potent α-glucosidase inhibitors. The target compounds were successfully synthesized and structurally chara...