Melatonin-loaded nanoparticles reduce cisplatin-induced oxidative stress and lymphopenia: An experimental study in rats.
This study aims to investigate the protective mechanisms of melatonin (Mel) and melatonin-loaded chitosan nanoparticles (ChitMelNPs) against cisplatin (CP)-induced oxidative stress and lymphopenia in rats. CP is a widely used chemotherapeutic drug known for its effectiveness in cancer treatment but associated with sign...