Ubiquitin C-hydrolase L1 as a cerebrospinal fluid and blood biomarker for prion diseases
Abstract Digital enzyme-linked immunosorbent assays are based on single-molecule array technology. In this study, ubiquitin C-terminal hydrolase L1 (UCH-L1) levels were measured in cerebrospinal fluid (CSF) and blood samples (serum or plasma) obtained from patients with sporadic Creutzfeldt–Jakob disease and fatal fami...