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Author

Shaden Haddad

2 papers indexed here

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Review Open access Oct 2026

FTO-Mediated m6A Demethylation in Insulin Resistance and Type 2 Diabetes: Tissue-Specific Mechanisms - a Narrative Review

In summary, FTO dysregulation may be involved in insulin resistance and metabolic risk factors associated with T2D, particularly given differences among genetic-association studies, experimental models, and human metabolic studies.

Hadil Shams Aldeen Alsagher, Shaden Haddad · 0 citations
Open access Oct 2026

Circulating FTO Protein Levels and β-Cell Function in Individuals with Different Metabolic Profiles: A Cross- Sectional Study

Background Obesity and type 2 diabetes mellitus are characterized by insulin resistance and progressive impairment of β-cell function. Fat mass and obesity-associated (FTO) protein, an m6A demethylase involved in metabolic regulation, has been linked to obesity. However, the relationship between circulating FTO protein...

Hadil Shams Aldeen Alsagher, Shaden Haddad · 0 citations

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