EF-P-Mediated Enhancement of Protein Synthesis: Cyclic Dipeptide Incorporation Using Mono- and Bisaminoacylated tRNAs.
Strategies for site-specific incorporation of noncanonical amino acids have advanced substantially, enabling access to proteins containing numerous analogues. That noted, many interesting analogues are not α-L-amino acids, and the incorporation of such compounds often requires the development and use of engineered ribo...