Development and evaluation of clobetasol propionate-loaded nanoliposomal hydrogel integrated with plant-derived microneedle-like microstructures for site-specific psoriasis therapy
The hyperkeratotic stratum corneum is a principal barrier to the efficient topical treatment of psoriasis and limits drug penetration and therapeutic efficacy. In this regard, the aim of this study was to prepare a new topical delivery system containing clobetasol propionate (CP)-encapsulating nanoliposomes dispersed...