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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Shan Qiang

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Open access Sep 2026

Senescence-associated transcriptional reprogramming in the tumor immune microenvironment: Mechanistic layers and therapeutic opportunities

The tumor immune microenvironment (TIME) is a principal determinant of tumor progression, metastatic dissemination, and therapeutic response. Cellular senescence, primarily through the senescence-associated secretory phenotype (SASP), progressively reshapes the TIME toward immunosuppressive and therapy-resistant states...

Xiao Yu, Jian-Lei Xing, Xu-Dong Zhao et al. · 0 citations
Open access Aug 2026

Metabolic-epigenetic rewiring of CCR5hi monocytes sustains long-term trained immunity against lethal sepsis

Findings identify a lactate-KAT2B-H3K18la epigenetic axis that orchestrates the long-term reprogramming of CCR5hi monocytes, highlighting CCR5hi monocytes as a promising therapeutic target for modulating innate immunity against lethal sepsis.

Lingqi Xu, Wenyan Hao, Yingyi Yang et al. · 0 citations

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