Shan-Shan Liu

Hepatic cholinergic T cell signaling mediates an adaptive response to alcohol-induced liver stress

Alcohol-associated liver disease (ALD) is a major cause of liver-related morbidity and mortality, yet no targeted, disease-modifying therapy exists and the immune mechanisms driving disease progression remain poorly defined. Acetylcholine-producing cholinergic immune cells have emerged as regulators of homeostasis acro...