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Open access Aug 2026

Triptolide Suppresses Tongue Squamous Cell Carcinoma Progression via PI3K–AKT Pathway Inhibition: An Integrative Network Pharmacology and Experimental Validation Study

This study is the first to demonstrate the pivotal role of the PI3K–AKT signaling pathway in mediating the antitumor effects of triptolide in tongue squamous cell carcinoma, providing a novel theoretical foundation for the development of traditional Chinese medicine‐based therapeutic strategies targeting this malignanc...

Shan Wang, Hong-Cheng Wei, Lin Jiang et al. · 0 citations

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