Shan-Yu Du

Inflammation-centered neurovascular–immune–metabolic remodeling in ischemic stroke: stage-dependent mechanisms, regulated cell death, and therapeutic translation

Ischemic stroke evolves beyond arterial occlusion through an inflammation-centered network linking neurovascular dysfunction, immune remodeling, metabolic reprogramming, and regulated cell death. These interactions are organized across the hyperacute, acute, subacute, and chronic phases. Hyperacute energy failure, exci...