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Shang-Hui Deng

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Conference Open access Sep 2026

Spot-Adaptive Structural Rectification for Spatially Resolved Transcriptomics Data Clustering

Spatially resolved transcriptomics integrates gene expression with spatial coordinates to decode tissue microenvironments. Existing methods predominantly utilize graph structures to model relationships between spots. However, their performance is bottlenecked by the reliability of gene feature graph, facing the followi...

Huan-Jia Zhao, Shang-Hui Deng, Shunfanyi Li et al. · 0 citations
Jul 2026

Hierarchical Graph Representation Learning From a Statistical Perspective for Generalizable and Interpretable Protein-Ligand Binding Affinity Prediction.

Protein-ligand binding affinity (PLA) prediction aims to guide rational drug design by estimating the strength of interaction. The effectiveness of the representation learning of protein and ligand is key to successful PLA prediction. To this end, attention mechanism, as a powerful architectural paradigm, has been intr...

Changming Yao, Shunfanyi Li, Shanghui Deng et al. · 0 citations

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