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Author

Shanjiang Zhao

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Open access Aug 2026

Follicle-stimulating hormone promotes energy metabolism in bovine granulosa cells through the FOXO1-ISG15 pathway to maintain the development of multiple follicles

A mammalian model of multi-follicular development using pFSH and integrated single-cell transcriptomics with functional analyses uncovered a regulatory axis governing the metabolism and proliferation of granulosa cells (GCs), revealing the pivotal role of the pFSH–FOXO1–ISG15 regulatory axis in orchestrating GC metabol...

Huan Wang, Zhihui Hu, Hua-Bin Zhu et al. · 0 citations

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