Shao-Feng Zhan

Deciphering the therapeutic mechanisms of Qingfei Litan prescription in acute lung injury: an integrated framework of UHPLC–MS/MS, systems pharmacology, machine learning, and in vivo validation

Background Acute lung injury (ALI) is primarily defined by hyper-inflammation and the breakdown of the alveolar-capillary barrier, frequently culminating in refractory respiratory failure. Current clinical interventions—predominantly glucocorticoids and supportive therapies—often yield suboptimal outcomes and are assoc...