Neuroimmune responses in neonatal hypoxic-ischemic encephalopathy: cellular roles, crosstalk, and therapeutic opportunities
Neonatal hypoxic-ischemic encephalopathy (HIE) is traditionally viewed as a consequence of acute oxygen and blood flow deprivation followed by excitotoxicity, oxidative stress, and neuronal death. However, growing evidence indicates that HIE is also a dynamic neuroimmune disorder in which immune cells actively shape in...