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Author

Sharmila Muthusethupathi

1 paper indexed here

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Review Aug 2026

Metabolism-driven hepatotoxicity of 5-fluorouracil: molecular mechanisms and future therapeutic directions.

5-Fluorouracil (5-FU) is a widely used chemotherapeutic agent for the treatment of various solid malignancies; however, its clinical application is also associated with hepatotoxicity. As the liver is the primary site of 5-FU metabolism, excessive accumulation of the drug and its metabolites can lead to hepatic injury...

Sharmila Muthusethupathi, D. Ezhilarasan · 0 citations

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