Author

Shawn R. Eagle

2 papers indexed here

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Oct 2026

Clinical cutoffs for plasma biomarkers to identify intracranial pathology in traumatic brain injury patients with Glasgow Coma Scale scores 13 to 15: a TRACK-TBI study.

OBJECTIVE The authors sought to identify plasma glial fibrillary acidic protein (GFAP) and ubiquitin c-terminal hydrolase-L1 (UCH-L1) cutoffs corresponding to a range of high positive predictive values (PPVs) for detecting intracranial pathology on CT and detecting pathology on MRI (when CT is negative) in patients who...

Shawn R. Eagle, John K. Yue, A. Puccio et al. · Journal of Neurosurgery · 1 citation

Review Open access Sep 2026

Clinical Utility of Structural Blood-Based Biomarkers in Pediatric Traumatic Brain Injury: A Focused Review of Glial Fibrillary Acidic Protein, Ubiquitin C-Terminal Hydrolase L1, and S100 Calcium-Binding Protein B.

BACKGROUND Blood-based biomarkers are becoming increasingly relevant for the diagnosis of acute traumatic brain injury (TBI) in adults, but they remain underutilized in children. There exists the need for high-quality evidence to support their use in defined clinical contexts. METHODS This review synthesizes recent e...

A. Fu, Mahmoud M. Elguindy, Angela Tang-Tan et al. · Pediatric Neurology · 0 citations