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Shawn R. Wadia

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Open access Sep 2026

EPHA2 and WNT reciprocally regulate MAPK-dependent gene expression in a pancreatic cancer model.

Phosphotyrosine-targeted mass spectrometry revealed robust phosphorylation of EPHA2 and EGFR upon Wnt inhibition, which suggests a Wnt-activated transcriptional repressor such as GATA3 that gates MAPK signaling in Wnt-high cancers.

Shawn R. Wadia, Chang-Yuan Hu, S. Patnaik et al. · 0 citations

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