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Author

Sheema Tasneem Mohamed

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Open access Oct 2026

Clinical Efficacy of Photodynamic Therapy and 1% Metformin Gel as Adjuncts to Scaling and Root Planing in the Treatment of Periodontitis: A Randomised Clinical Trial

Introduction: Photodynamic Therapy (PDT) utilises lightactivated Photosensitisers (PSs) to generate Reactive Oxygen Species (ROS) disrupting bacterial biofilms and eliminating pathogens with minimal toxicity. Metformin enhances bacterial clearance, suppresses Lipopolysaccharide (LPS)- induced inflammation, and stimulat...

Sai Prathyusha Bantupalli, Anil Kumar Kancharla, Anwesh Reddy Nandigam et al. · 0 citations

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