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Author

Shelby C. Osburn

2 papers indexed here

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Open access Sep 2026

Biomechanical strain alters the microRNA cargo of primary myogenic cell-derived extracellular vesicles associated with a differentiation phenotype

Extracellular vesicles (EVs) are membrane-bound vesicles that regulate intercellular signaling by transporting cellular cargo including RNAs, proteins, and lipids. In recent years, EVs have emerged as promising biologic therapeutics for musculoskeletal repair, recapitulating many of the benefits of mesenchymal stromal...

K. Williams, L. Chubb, Shelby C. Osburn et al. · 0 citations
Open access Aug 2026

Aged Mitochondrial DNA Is Associated With Aberrant Acute Exercise‐Induced Redox Responses in Human Skeletal Muscle

Redox imbalances and mitochondrial dysfunction are key contributors to age‐related declines in skeletal muscle and may contribute to impaired exercise responsiveness. Here, we investigated the influence of aging on skeletal muscle redox at rest and in response to acute exercise, examining how mitochondrial quality and...

Bradley A. Ruple, Nicholas A Carlini, Jason S. Kofoed et al. · 0 citations

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