Rosmarinic acid alleviates renal tubular injury in obesity-related hypertension by inhibiting the IL-18R1/MYD88/IRAK4 pathway.
Renal tubular injury induced by pro-inflammatory cytokines is the key pathological basis for the progression of obesity-related hypertensive (OBH) nephropathy. Rosmarinic acid (RA) is an important active ingredient in many traditional Chinese medicines and exhibits a variety of pharmacological properties in the treatme...