Open access
Sep 2026
ProRB: a structure-free unified framework for joint prediction and design of protein–RNA interactions
ProRB is introduced, a unified sequence-based framework that jointly estimates protein–RNA binding affinity, predicts binding interfaces in proteins and RNAs, and generates protein-binding RNA sequences from protein sequences that provides a scalable unified model for decoding the protein–RNA interaction and engineerin...
Yiming Xue, Xiao-Jian Liu, Wei-Min Zhu et al.
· Nucleic Acids Research · 0 citations