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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Sheng-Huei Wang

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Open access Aug 2026

Chronic Hypoxia-Induced Reprogramming of Smooth Muscle Cells: Insights into Transcription Factors, Cellular Stresses, and Therapeutic Implications

Background/Objectives: Chronic hypoxia promotes a shift in smooth muscle cells from a quiescent, contractile state to a highly proliferative phenotype, contributing to persistent vascular remodeling. This study examines primary human esophageal smooth muscle cells (HEsSMCs) exposed to hypoxia mimics, desferoxamine (DFO...

Sheng-Huei Wang, Yuan-Ming Tsai, Shu-Ting Liu et al. · 0 citations

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