Author

Sheng-Shan Xu

2 papers indexed here

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Open access Sep 2026

Synergistic effect of insulin resistance and glycemic variability on mortality in ICU patients with gastrointestinal bleeding: impact of the TyG-GVI index and development of an explainable web-based clinical calculator

Objective To investigate the association between the composite Triglyceride-Glucose Index combined with Glycemic Variability (TyG-GVI) and early-death risk in ICU patients with gastrointestinal bleeding, and evaluate whether integrating this biomarker into ensemble-learning models improves prognostic performance. Metho...

Yan-Qiu Jiang, Ke-Yan Guo, Ke-Xin Jiang et al. · Frontiers in Endocrinology · 0 citations

Review Open access Aug 2026

Liver microenvironment-driven immunosuppressive niche in colorectal cancer liver metastasis and its therapeutic remodeling

Colorectal cancer liver metastasis is the most frequent and clinically important pattern of distant spread in colorectal cancer and remains a major determinant of poor prognosis and treatment failure. In the era of immunotherapy, liver metastasis has emerged as an organ-specific barrier to effective antitumor immune re...

Zi-Jing Liu, Jia Liu, Sheng-Shan Xu et al. · Frontiers in Immunology · 0 citations