PPIA-CD147 Interaction Mediates Immune-induced Cardiomyocyte Hypertrophy After Cardiac Xenotransplantation.
BACKGROUND Pathological myocardial hypertrophy constitutes a major impediment to the prolonged survival of heart xenotransplantation. Conventional approaches, including intensive antihypertensive therapy and growth factor receptor knockout, have demonstrated limited efficacy in mitigating this maladaptive remodeling. I...